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Results for "

Chinese medicinal

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AP-1 (1) Autophagy (1) COX (1) FLT3 (1) HDAC (1) Interleukin Related (1) mAChR (1) NF-κB (2) NO Synthase (1) p38 MAPK (1) TNF Receptor (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (5) Metabolic Disease (1) Neurological Disease (1)

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Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N1371

Clinodiside A

Others Infection

Clinodiside A is isolated from the Chinese medicinal herb Clinopodium chinensis .

Clinodiside A	Others	Infection
Clinodiside A is isolated from the Chinese medicinal herb Clinopodium chinensis .

HY-N2382

Polyphyllin H	Others	Neurological Disease Inflammation/Immunology
Polyphyllin H has been widely used in traditional Chinese medicinal preparations to treat inflammation, fracture and convulsion .

HY-N10947

Lanosta-7,9(11),24-trien-3β,15α-dihydrcxy-26-oic acid	Others	Others
Lanosta-7,9(11),24-trien-3β,15α-dihydrcxy-26-oic acid (compound 2) is a nature product that could be isolated from the Chinese medicinal fungus Ganoderma lucidurn .

HY-N10913

Chloranthalactone B	AP-1 p38 MAPK NO Synthase TNF Receptor COX Interleukin Related	Inflammation/Immunology
Chloranthalactone B, a lindenane-type sesquiterpenoid, is a nature product that could be isolated from Chinese medicinal herb Sarcandra glabra. Chloranthalactone B inhibits the production of inflammatory mediators by inhibiting the AP-1 and p38 MAPK pathways .

HY-N12034

Picropodophyllin-β-D-glucoside

Others Others

Picropodophyllin-β-D-glucoside (compound 3) is a podophyllotoxin glucoside isolated from Chinese medicinal plants .
HY-N8496

Clinopodiside A

Others Others

Clinopodiside A, a triterpenoid saponin, is isolated from Clinopodium polycephalum which is a popular Chinese traditional medicinal herb .

Picropodophyllin-β-D-glucoside	Others	Others
Picropodophyllin-β-D-glucoside (compound 3) is a podophyllotoxin glucoside isolated from Chinese medicinal plants .

Clinopodiside A	Others	Others
Clinopodiside A, a triterpenoid saponin, is isolated from Clinopodium polycephalum which is a popular Chinese traditional medicinal herb .

HY-N3980

Guaiol Champacol; Guaiac alcohol	Autophagy	Infection Cancer
Guaiol is a sesquiterpene alcohol that has been found in several traditional Chinese medicinal plants and has antiproliferative, pro-autophagic, insect repellent, and insecticidal biological activities .

HY-N10387

Glucodichotomine B	Others	Cancer
Glucodichotomine B (Compound 13) is a natural product which can be isolated from the roots of Chinese medicinal plant Stellaria dichotoma L. var. lanceolata. Glucodichotomine B shows antitumor activity .

HY-N2936

Bi-linderone	Others	Others
Bi-linderone is isolated as racemate from the traditional Chinese medicinal plant Lindera aggregata. Bi-linderone has activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 μg/mL .

HY-N0071

Crotonoside Isoguanosine	FLT3 HDAC	Cancer
Crotonoside is isolated from Chinese medicinal herb, Croton. Crotonoside inhibits FLT3 and HDAC3/6, exhibits selective inhibition in acute myeloid leukemia (AML) cells. Crotonoside could be a promising new lead compound for the research of AML .

HY-N0758

Barlerin 8-O-Acetyl shanzhiside methyl ester	NF-κB	Inflammation/Immunology
Barlerin (8-O-Acetyl shanzhiside methyl ester) is an iridoid glucoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant in Xi-zang. Barlerin (8-O-Acetyl shanzhiside methyl ester) could inhibt NF-κB.

HY-N0029

Forsythoside B 5 Publications Verification	TNF Receptor NF-κB	Inflammation/Immunology
Forsythoside B is a phenylethanoid glycoside isolated from Forsythia suspensa (Thunb.) Vahl, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation. Forsythoside B could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB.

HY-118736

Ganodermic acid S	Others	Cardiovascular Disease
Ganodermic acid S is an oxygenated triterpenoid, that can be isolated from the Chinese medicinal fungus Ganoderma lucidum (Fr.) Karst (Polyporaceae). Ganodermic acid S exerts a concentration dependent inhibition on the response of human gel-filtered platelets (GFP) to U-46619 (HY-108566), a thromboxane (TX) A2 mimetic .

HY-N2499

Dehydrotumulosic acid	Others	Metabolic Disease
Dehydrotumulosic acid is one of the effective constituents of Poria cocos. Poria cocos, a popular Chinese medicinal herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body .

HY-N0584A

Anisodamine hydrobromide 6-Hydroxyhyoscyamine hydrobromide	mAChR	Inflammation/Immunology
Anisodamine hydrobromide (6-Hydroxyhyoscyamine hydrobromide), a belladonna alkaloid, is a non-subtype-selective muscarinic and a nicotinic cholinoceptor antagonist. Anisodamine hydrobromide shows antioxidant, anti-inflammatory properties .

Cat. No.	Product Name

HY-L163

FDA-Approved Traditional Chinese Medicine Active Compound Library	320 compounds
Traditional Chinese medicine provides abundant natural resources for medicinal compounds, which are often considered effective and safe for drug discovery. Traditional Chinese medicine is based on the principle of "multiple components, multiple targets, and multiple pathways", and naturally has multiple pharmacological effects. As herbal medicine, the secondary plant metabolites in Chinese herbal medicine play an important role in alleviating many diseases in Traditional medicine and folk use. Therefore, the identification of traditional Chinese medicine derived compounds is also an important process in drug development and a necessary factor in dissecting the overall mechanism of action of traditional Chinese medicine. FDA listed compounds have completed extensive preclinical and clinical studies, exhibiting good biological activity, safety, and bioavailability. MCE designs a unique collection of 320 FDA-approved traditional Chinese medicine active compounds, including flavonoids, polyphenols, alkaloids, terpenoids, and other structural types. It is a good tool for drug reuse and screening drugs from traditional Chinese medicine sources.

FDA-Approved Traditional Chinese Medicine Active Compound Library

320 compounds

Traditional Chinese medicine provides abundant natural resources for medicinal compounds, which are often considered effective and safe for drug discovery. Traditional Chinese medicine is based on the principle of "multiple components, multiple targets, and multiple pathways", and naturally has multiple pharmacological effects. As herbal medicine, the secondary plant metabolites in Chinese herbal medicine play an important role in alleviating many diseases in Traditional medicine and folk use. Therefore, the identification of traditional Chinese medicine derived compounds is also an important process in drug development and a necessary factor in dissecting the overall mechanism of action of traditional Chinese medicine. FDA listed compounds have completed extensive preclinical and clinical studies, exhibiting good biological activity, safety, and bioavailability.

MCE designs a unique collection of 320 FDA-approved traditional Chinese medicine active compounds, including flavonoids, polyphenols, alkaloids, terpenoids, and other structural types. It is a good tool for drug reuse and screening drugs from traditional Chinese medicine sources.

HY-L065

Traditional Chinese Medicine Active Compound Library	2845 compounds
Chinese herbal therapy is an important part of Traditional Chinese Medicine (TCM). It has been used for centuries in China, where herbs are considered fundamental therapy for many acute and chronic conditions. Many studies indicated TCM exerted an overall regulatory effect via multi-component and multi-target network. Active components from Traditional Chinese Medicine possess many medicinal properties such as antioxidant, anti-cancer, and anti-bacterial effects, which makes it an important source of new drugs. Nearly 200 modern medicines have been developed either directly or indirectly from the plants used as medicines in China. For example, artemisinin, used in multidrug resistant malaria, was first isolated from the Chinese herb Artemisia annua L. Today, scientists continue to identify compounds in Chinese herbal remedies that may be useful in the development of new therapeutic agents applicable in Western medicine. MCE designs a unique collection of 2845 active compounds of Chinese Herbal Medicines. MCE Traditional Chinese Medicine Active Compound Library is a useful tool for discovery new drugs from TCM.

Traditional Chinese Medicine Active Compound Library

2845 compounds

Chinese herbal therapy is an important part of Traditional Chinese Medicine (TCM). It has been used for centuries in China, where herbs are considered fundamental therapy for many acute and chronic conditions. Many studies indicated TCM exerted an overall regulatory effect via multi-component and multi-target network. Active components from Traditional Chinese Medicine possess many medicinal properties such as antioxidant, anti-cancer, and anti-bacterial effects, which makes it an important source of new drugs. Nearly 200 modern medicines have been developed either directly or indirectly from the plants used as medicines in China. For example, artemisinin, used in multidrug resistant malaria, was first isolated from the Chinese herb Artemisia annua L. Today, scientists continue to identify compounds in Chinese herbal remedies that may be useful in the development of new therapeutic agents applicable in Western medicine.

MCE designs a unique collection of 2845 active compounds of Chinese Herbal Medicines. MCE Traditional Chinese Medicine Active Compound Library is a useful tool for discovery new drugs from TCM.

Clinodiside A	Infection Triterpenes other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields	Others
Clinodiside A is isolated from the Chinese medicinal herb Clinopodium chinensis .

Polyphyllin H	other families Source classification Plants Steroids	Others
Polyphyllin H has been widely used in traditional Chinese medicinal preparations to treat inflammation, fracture and convulsion .

Lanosta-7,9(11),24-trien-3β,15α-dihydrcxy-26-oic acid	Triterpenes Structural Classification Terpenoids Source classification Polyporaceae Plants	Others
Lanosta-7,9(11),24-trien-3β,15α-dihydrcxy-26-oic acid (compound 2) is a nature product that could be isolated from the Chinese medicinal fungus Ganoderma lucidurn .

Chloranthalactone B	Structural Classification Terpenoids Sesquiterpenes Source classification Sarcandra glabra (Thunb.) Nakai Chloranthaceae Plants	AP-1 p38 MAPK NO Synthase TNF Receptor COX Interleukin Related
Chloranthalactone B, a lindenane-type sesquiterpenoid, is a nature product that could be isolated from Chinese medicinal herb Sarcandra glabra. Chloranthalactone B inhibits the production of inflammatory mediators by inhibiting the AP-1 and p38 MAPK pathways .

Picropodophyllin-β-D-glucoside	Structural Classification Sinopodophyllum hexandrum (Royle) Ying Source classification Lignans Phenylpropanoids Plants Berberidaceae Saccharides Monosaccharides	Others
Picropodophyllin-β-D-glucoside (compound 3) is a podophyllotoxin glucoside isolated from Chinese medicinal plants .

Clinopodiside A	Triterpenes Classification of Application Fields Terpenoids Labiatae Source classification Other Diseases Plants Helenium amarum (Raf.) H.Rock Disease Research Fields	Others
Clinopodiside A, a triterpenoid saponin, is isolated from Clinopodium polycephalum which is a popular Chinese traditional medicinal herb .

Guaiol Champacol; Guaiac alcohol	Infection Natural Products Classification of Application Fields Source classification Distemonanthus benthamianus Baill. Plants Compositae Disease Research Fields	Autophagy
Guaiol is a sesquiterpene alcohol that has been found in several traditional Chinese medicinal plants and has antiproliferative, pro-autophagic, insect repellent, and insecticidal biological activities .

Bi-linderone	Structural Classification Natural Products Source classification Plants Lauraceae Lindera aggregata (Sims) Kosterm.	Others
Bi-linderone is isolated as racemate from the traditional Chinese medicinal plant Lindera aggregata. Bi-linderone has activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 μg/mL .

Crotonoside Isoguanosine	Alkaloids Structural Classification Classification of Application Fields Croton tiglium Linn. Source classification Euphorbiaceae Plants Disease Research Fields Cancer	FLT3 HDAC
Crotonoside is isolated from Chinese medicinal herb, Croton. Crotonoside inhibits FLT3 and HDAC3/6, exhibits selective inhibition in acute myeloid leukemia (AML) cells. Crotonoside could be a promising new lead compound for the research of AML .

Barlerin 8-O-Acetyl shanzhiside methyl ester	Iridoids Classification of Application Fields Terpenoids Labiatae Source classification Plants Inflammation/Immunology Disease Research Fields Helenium radiatum (Less.) Bierner	NF-κB
Barlerin (8-O-Acetyl shanzhiside methyl ester) is an iridoid glucoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant in Xi-zang. Barlerin (8-O-Acetyl shanzhiside methyl ester) could inhibt NF-κB.

Forsythoside B 5 Publications Verification	Structural Classification Classification of Application Fields Oleaceae Simple Phenylpropanols Source classification Phenols Polyphenols Phenylpropanoids Plants Forsythia suspensa (Thunb.) Vahl Inflammation/Immunology Disease Research Fields	TNF Receptor NF-κB
Forsythoside B is a phenylethanoid glycoside isolated from Forsythia suspensa (Thunb.) Vahl, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation. Forsythoside B could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB.

Ganodermic acid S	Triterpenes Structural Classification Microorganisms Ketones, Aldehydes, Acids Terpenoids Source classification	Others
Ganodermic acid S is an oxygenated triterpenoid, that can be isolated from the Chinese medicinal fungus Ganoderma lucidum (Fr.) Karst (Polyporaceae). Ganodermic acid S exerts a concentration dependent inhibition on the response of human gel-filtered platelets (GFP) to U-46619 (HY-108566), a thromboxane (TX) A2 mimetic .

Dehydrotumulosic acid	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Polyporaceae Metabolic Disease Poria cocos Plants Disease Research Fields	Others
Dehydrotumulosic acid is one of the effective constituents of Poria cocos. Poria cocos, a popular Chinese medicinal herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body .

Anisodamine hydrobromide 6-Hydroxyhyoscyamine hydrobromide	Alkaloids Pyrrole Alkaloids Classification of Application Fields Anisodus tanguticus (Maxinowicz) Pascher Source classification Plants Solanaceae Disease Research Fields Inflammation/Immunology	mAChR
Anisodamine hydrobromide (6-Hydroxyhyoscyamine hydrobromide), a belladonna alkaloid, is a non-subtype-selective muscarinic and a nicotinic cholinoceptor antagonist. Anisodamine hydrobromide shows antioxidant, anti-inflammatory properties .

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